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Sleep

The peptides readers look up for sleep, and whether each can be prescribed or compounded in the U.S. today. Every status below names the FDA document it rests on.

Prescribable now

  • Sermorelin

    Legal to compound

    Evidence: Small studies

    A short copy of the hormone that tells the pituitary to release growth hormone. Small 1990s studies show it raises growth hormone; none tested it against placebo for aging, body composition or sleep. Read the Sermorelin guide

    Component of an FDA-approved drug (GEREF, sermorelin acetate). FDA determined in 2013 that GEREF was not withdrawn from sale for reasons of safety or effectiveness.

    Source:FDA document, read September 2026.

    161 sellers we track publish a monthly price for it

Sellers for sleep

The licensed telehealths we have reviewed that prescribe Sermorelin for sleep. Each links to the seller and to our review of it.

Disclosure: This Peptide is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. How we make money.

  1. 50 Stars Health
    PrescribesSermorelin
  2. Actin
    PrescribesSermorelin
  3. AgelessRx
    PrescribesSermorelin
  4. AHBARx
    PrescribesSermorelin
  5. Alan Meds
    PrescribesSermorelin
  6. Alternate Health Club
    PrescribesSermorelin
  7. Amble
    PrescribesSermorelin
  8. Apex MD
    PrescribesSermorelin
  9. Arc-1
    PrescribesSermorelin
  10. Ark Health
    PrescribesSermorelin
  11. ARSYNL Rx
    PrescribesSermorelin
  12. Auren Rx
    PrescribesSermorelin
  13. Avono Health
    PrescribesSermorelin
  14. Bayan Health
    PrescribesSermorelin
  15. Bloom MD
    PrescribesSermorelin
  16. bmiMD
    PrescribesSermorelin
  17. Bodybuilding Health+
    PrescribesSermorelin
  18. Breeze Meds
    PrescribesSermorelin
  19. Brello Health
    PrescribesSermorelin
  20. Brightmeds
    PrescribesSermorelin
  21. Concierge MD LA
    PrescribesSermorelin
  22. Contour Health
    PrescribesSermorelin
  23. CoreAge Rx
    PrescribesSermorelin
  24. Direct Meds
    PrescribesSermorelin
  25. Eden
    PrescribesSermorelin
  26. EdgeRx
    PrescribesSermorelin
  27. Effecty
    PrescribesSermorelin
  28. ElitePhysiqMD
    PrescribesSermorelin
  29. ElleS
    PrescribesSermorelin
  30. EllieMD
    PrescribesSermorelin
  31. Embody
    PrescribesSermorelin
  32. Enhanced
    PrescribesSermorelin
  33. EOS Health
    PrescribesSermorelin
  34. Fitish
    PrescribesSermorelin
  35. FormBlends
    PrescribesSermorelin
  36. Found Youth
    PrescribesSermorelin
  37. Fridays
    PrescribesSermorelin
  38. Gala
    PrescribesSermorelin
  39. Genesis Health
    PrescribesSermorelin
  40. Get Thin MD
    PrescribesSermorelin
  41. Gimme Care
    PrescribesSermorelin
  42. Glam Health
    PrescribesSermorelin
  43. GobyMeds
    PrescribesSermorelin
  44. Goldspan Health
    PrescribesSermorelin
  45. Good Girl Rx
    PrescribesSermorelin
  46. Harbor
    PrescribesSermorelin
  47. He & She MD
    PrescribesSermorelin
  48. Heally
    PrescribesSermorelin
  49. HealthHub
    PrescribesSermorelin
  50. HealthOn
    PrescribesSermorelin
  51. HealthRX
    PrescribesSermorelin
  52. HealthSource
    PrescribesSermorelin
  53. Heros Health
    PrescribesSermorelin
  54. Hone Health
    PrescribesSermorelin
  55. Idgie Health
    PrescribesSermorelin
  56. Immortals
    PrescribesSermorelin
  57. Invigor Medical
    PrescribesSermorelin
  58. Iron Med RX
    PrescribesSermorelin
  59. iThriveMD
    PrescribesSermorelin
  60. Ivim Health
    PrescribesSermorelin
  61. Ivologist
    PrescribesSermorelin
  62. Jently
    PrescribesSermorelin
  63. Joi + Blokes
    PrescribesSermorelin
  64. June Health
    PrescribesSermorelin
  65. Kin Meds
    PrescribesSermorelin
  66. Kongo
    PrescribesSermorelin
  67. LaSara Medical Group
    PrescribesSermorelin
  68. Lean Meds
    PrescribesSermorelin
  69. Levers Health
    PrescribesSermorelin
  70. LifeVine Wellness
    PrescribesSermorelin
  71. Longevixx
    PrescribesSermorelin
  72. Loop Health
    PrescribesSermorelin
  73. Lttl
    PrescribesSermorelin
  74. Lumora
    PrescribesSermorelin
  75. Luvo Health
    PrescribesSermorelin
  76. MadeMed
    PrescribesSermorelin
  77. MangoRx
    PrescribesSermorelin
  78. Maximus
    PrescribesSermorelin
  79. Medro
    PrescribesSermorelin
  80. Meto
    PrescribesSermorelin
  81. Midi Health
    PrescribesSermorelin
  82. Mondae
    PrescribesSermorelin
  83. MyDrHank
    PrescribesSermorelin
  84. Nex Gen Health Rx
    PrescribesSermorelin
  85. NiceRx
    PrescribesSermorelin
  86. Nova
    PrescribesSermorelin
  87. Nova MD
    PrescribesSermorelin
  88. Nu Image Medical
    PrescribesSermorelin
  89. NuBloom
    PrescribesSermorelin
  90. Nucific
    PrescribesSermorelin
  91. Oak
    PrescribesSermorelin
  92. Obu Health
    PrescribesSermorelin
  93. Pallas Health
    PrescribesSermorelin
  94. PauseRX
    PrescribesSermorelin
  95. PepHaūs
    PrescribesSermorelin
  96. Pepti
    PrescribesSermorelin
  97. PeterMD
    PrescribesSermorelin
  98. PlexusDx
    PrescribesSermorelin
  99. Pomegranate Health
    PrescribesSermorelin
  100. PrescribedRX
    PrescribesSermorelin
  101. PreventiveMD
    PrescribesSermorelin
  102. Raeliva
    PrescribesSermorelin
  103. ReadyRx
    PrescribesSermorelin
  104. Regenics
    PrescribesSermorelin
  105. Rehydra+ Wellness
    PrescribesSermorelin
  106. REMEVi
    PrescribesSermorelin
  107. Revive Longevity
    PrescribesSermorelin
  108. Rewinding RX
    PrescribesSermorelin
  109. Rex MD
    PrescribesSermorelin
  110. RNK Health
    PrescribesSermorelin
  111. Rugiet Health
    PrescribesSermorelin
  112. RxION Health
    PrescribesSermorelin
  113. RxPepsDirect
    PrescribesSermorelin
  114. RxSaludable
    PrescribesSermorelin
  115. RxSpan MD
    PrescribesSermorelin
  116. Rylo Health
    PrescribesSermorelin
  117. ShedRx
    PrescribesSermorelin
  118. SkinnyRx
    PrescribesSermorelin
  119. Stealth Health
    PrescribesSermorelin
  120. Strut Health
    PrescribesSermorelin
  121. SynergenX Health
    PrescribesSermorelin
  122. Synergy Rx
    PrescribesSermorelin
  123. System Labs
    PrescribesSermorelin
  124. TelePeptide
    PrescribesSermorelin
  125. TeleZen MD
    PrescribesSermorelin
  126. The Edit
    PrescribesSermorelin
  127. TMates
    PrescribesSermorelin
  128. TrueMe
    PrescribesSermorelin
  129. Try Ageless
    PrescribesSermorelin
  130. Tyde Wellness
    PrescribesSermorelin
  131. VigorMeds
    PrescribesSermorelin
  132. Vita Bella
    PrescribesSermorelin
  133. Vyora Wellness
    PrescribesSermorelin
  134. Vytora Health
    PrescribesSermorelin
  135. Wellorithm
    PrescribesSermorelin
  136. Welludr
    PrescribesSermorelin
  137. WePeptideRx
    PrescribesSermorelin
  138. Whoosh Wellness
    PrescribesSermorelin
  139. Woodwork
    PrescribesSermorelin
  140. Yes Clinic
    PrescribesSermorelin
  141. YourEra
    PrescribesSermorelin
  142. YourHealthRx
    PrescribesSermorelin
  143. Yucca Health
    PrescribesSermorelin
  144. ZYP Medical
    PrescribesSermorelin

Ordered by how many of these peptides each seller prescribes, then by name. A partnership never changes the order.

Research only

These are not on an FDA list that allows compounding, or we have not yet read their status. We cover the research on them and link no seller.

Research on sleep

  1. Selank: what the human trials actually foundSelank is one of the few research peptides tested in people. Three Russian trials, about 190 patients, and no replication anywhere else.
  2. DSIP Dosage: The Doses Used in the Human StudiesFour human studies used the same figure: 25 nanomoles per kilogram, into a vein. None used milligrams, none injected under the skin, and both sleep studies at that dose called the benefit weak.
  3. Semaglutide Insomnia: What the Labels and Sleep Studies RecordInsomnia does not appear in the Wegovy or Ozempic label, and no randomized trial has measured it. A matched cohort of 23,386 people looked for it and found no increased risk, while the studies that measured sleep found it improving.
  4. Zepbound for Sleep Apnea: What the SURMOUNT-OSA Trials FoundZepbound is approved for moderate to severe obstructive sleep apnea in adults with obesity. In two year-long trials, breathing events fell by about half, and the weight loss is the likely reason.
  5. Sermorelin vs HGH: A Signal to the Pituitary or the Hormone ItselfSermorelin asks the pituitary to release growth hormone; HGH is the hormone. No trial has compared them head to head in adults, and their legal and evidence records differ sharply.
  6. CJC 1295 and Ipamorelin: What Human Studies Exist for the PairEach peptide has a thin human record of its own. No trial of the two taken together has been published or registered, and FDA has flagged safety concerns about both.
  7. Does Sermorelin Work? What the Human Studies MeasuredSmall studies in older men show sermorelin raises growth hormone, and at twice-daily doses IGF-1. No placebo-controlled trial has shown it changes muscle, fat or sleep in adults.
  8. DSIP Peptide: What Delta Sleep-Inducing Peptide Trials in People FoundOne small double-blind study found better sleep; two others found effects too weak to matter. All used IV doses. The FDA calls the evidence inconclusive, and DSIP is research-only.
  9. Growth Hormone Peptides: GHRH Analogs vs Ghrelin Mimetics, and Their EvidenceEvery growth hormone peptide works through one of two receptors. Only one holds a current FDA approval, and the FDA flags several of the rest for safety risks.
  10. Ipamorelin: What the Human Evidence Actually ShowsOne dosing study in healthy men and one bowel-surgery trial that missed its goal. That is the published human record for a peptide sold for muscle, fat loss and sleep.
  11. Ipamorelin Side Effects: What the Few Human Trials RecordedTwo small human studies, both by vein, make up the record. The FDA flags serious events with intravenous use, and nobody has measured the injection people actually buy.
  12. Peptides for Sleep: What Human Studies of GHRH and DSIP FoundGHRH deepened sleep in young men, worsened it in young women and did less in older adults. DSIP, the peptide named for sleep, showed little benefit in insomnia.
  13. Sermorelin Before and After: What Trials Measured Over Weeks and MonthsThe sermorelin studies published no photos. Here is what the studies did measure at 2 weeks, 6 weeks, 16 weeks and a year, and which changes never showed up.
  14. Sermorelin Dosage: What the Approved Product and Trials Actually UsedA single diagnostic dose, a nightly pediatric regimen, and two small studies in older men. That is the whole documented record for sermorelin dosing.
  15. Sermorelin Nasal Spray: Does GHRH Work Without an Injection?The only approved sermorelin was an injection. Nasal studies of the same molecule found 3–5% reached the blood, and no study has tested it by mouth or as a troche.
  16. Sermorelin Side Effects: What the Trials and FDA Record ReportFlushing and injection-site pain are the reported side effects. The harder truth is how small the safety record is, especially for the adults who use it today.
  17. Sermorelin vs Ipamorelin: Two Very Different Evidence RecordsNo head-to-head trial turns up in PubMed. One was an approved drug with a year-long pediatric trial; the other has a dosing study and a trial that missed its goal.
  18. Tesamorelin vs Sermorelin: Two GHRH Analogs With Very Different EvidenceBoth copy the hormone that tells the pituitary to release growth hormone. One has FDA-approved trials in more than 800 people; the other has two small studies in older men.