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Rylo Health

Rylo charges one flat price a month with no membership and free shipping. Every product page opens on the quarterly tab instead.

Review by Leah Garner, clinical-evidence editor · Updated September 2026

The short version

The commercial terms are among the plainest in this category. One price a month, no membership, cancel any month, refundable until a physician has seen you. The catch is presentational. Each page defaults to a prepaid rate, and the saving beside it is measured against the monthly figure the page is not showing.

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Lowest listed: Semaglutide injection, from $139/mo

All 50 states

Visit Rylo Health →

Rylo Health is a cash-pay service selling compounded peptides as monthly protocols. Its navigation lists five: tirzepatide, semaglutide, NAD+, sermorelin and glutathione. A sixth, a GHK-Cu protocol, has its own page but does not appear in that list. It says it operates in all 50 states and describes itself as HIPAA compliant.

What Rylo Health prescribes, by goal

Weight

  • SemaglutideFDA-approved
    • Injection (compounded)From $139/mo
  • TirzepatideFDA-approved
    • Injection (compounded)From $229/mo

Compounded semaglutide is $139 a month and tirzepatide $229. Both are described as including everything needed to dose at home, with no membership and no shipping charge. No milligram strength is printed for either.

Longevity

  • GlutathioneLegal to compound
    • Injection (compounded)From $149/mo
  • NAD+Legal to compound
    • Injection (compounded)From $219/mo

NAD+ runs $219 a month and glutathione $149. The GHK-Cu protocol, at $199, is sold as a topical rather than an injection, and is the one product missing from the site's own navigation.

Recovery

  • GHK-CuLegal to compound
    • Topical (compounded)From $199/mo
  • SermorelinLegal to compound
    • Injection (compounded)From $249/mo

Sermorelin is $249 a month. The page describes it as prompting the pituitary to release growth hormone rather than replacing it, and says a doctor sets and adjusts the dose over time.

Sleep

  • SermorelinLegal to compound
    • Injection (compounded)From $249/mo

The same sermorelin protocol is sold for sleep, on the reasoning that most natural growth hormone release happens at night. The schedule is printed as one dose a day, taken at bedtime; no strength in milligrams appears beside it.

Each “From” figure is the seller’s own starting price, in the unit the seller states. Where a required fee or a package length changes what one month costs, the smaller line under it is our arithmetic, not a figure the seller prints. Compounded preparations are not FDA-approved.

Who prescribes

A licensed clinician

No prescriber is named. The site says a US-licensed, board-certified physician reviews and approves every prescription before it ships, and that the review happens within 24 hours. Who that physician is, and what practice they work for, is never stated. The pharmacy is described as a licensed 503A compounding pharmacy and is not named either.

The intake is a five-minute questionnaire covering health history, current medications and goals. The site is explicit that there is no video call and no waiting room; a phone visit is not mentioned either. A physician then reads the answers and decides. After that, ongoing access is by text, which the site advertises as reaching a real person rather than a bot. Supplies are restocked every month with the medication.

Are labs required?

Not asked for

No bloodwork is requested anywhere in the process the site describes, and no lab charge appears. The five-minute questionnaire is the whole of what a physician sees before deciding.

Ready to start with Rylo Health?

Lowest listed price: Semaglutide injection, from $139/mo. Confirm it on the seller’s own site.

What it claims, and what it cites

The medical copy is hedged where it should be. Sermorelin is said to support deeper sleep, recovery and body composition. The page also carries a real contraindication list: not while pregnant or breastfeeding, and not for people with active cancer or certain uncontrolled endocrine disorders. Compounded status is stated plainly, including that the FDA does not evaluate compounded drugs for safety, effectiveness or quality. The claim that deserves a closer look is about manufacturing. The site says every batch gets full chemistry and microbiology testing, and prints three status badges beside that: sterility passed, endotoxin passed, potency verified. No certificate of analysis, batch number or date sits behind them, so what is shown is a promise rather than a result.

On Rylo Health’s siteSource it gives
On Rylo Health’s site“Every batch goes through a real lab first. Not sampled. Not skipped.”Source it givesThree badges read Passed, Passed and Verified, with no certificate of analysis, batch number or date behind them
On Rylo Health’s site“A US-licensed physician reviews and approves every prescription”Source it givesStated on each product page; no physician is named and no practice is identified
On Rylo Health’s site“From a licensed 503A compounding pharmacy”Source it givesStated on each product page; the pharmacy is not named
On Rylo Health’s site“Available in all 50 states”Source it givesNone given

Sold by Rylo Health, not listed here

MOTS-c
On no 503A list (not in Categories 1–3 of the May 14, 2026 update). The FDA's compounding advisory committee voted 7–5 (two abstentions) in July 2026 to favor listing it; the vote is a recommendation, not binding on the FDA, and pharmacies may not compound it until final rulemaking.
The GHK-Cu protocol's place in the catalog
It is priced and has a product page, but the site's own Protocols list omits it, so a reader browsing the navigation will not find it.

How it bills

One flat price a month per protocol, and the site repeats it: no membership fees, free two-day shipping in unmarked packaging, and cancellation any month. Semaglutide is $139, glutathione $149, GHK-Cu $199, NAD+ $219, tirzepatide $229 and sermorelin $249. Refunds are generous at the point that matters, with everything refundable up to the first physician consultation. What the pages do not do is open on those numbers. Each one defaults to a quarterly tab: sermorelin shows $183 a month billed $549, GHK-Cu $166 billed $499, glutathione $133 billed $399. Beside each sits a saving, and each saving is calculated against the monthly rate the tab is hiding.

Availability: All 50 states

For and against

  • For: One flat monthly price, stated as such
  • For: No membership fee anywhere
  • For: Free two-day shipping in unmarked packaging
  • For: Refundable until a physician has reviewed you
  • For: Supplies restocked with the medication
  • Against: Every page opens on the prepaid quarterly rate
  • Against: The saving is measured against a hidden figure
  • Against: No physician and no pharmacy is named
  • Against: Batch testing is shown as badges, not certificates
  • Against: No milligram strength on any product

The evidence behind what it sells

Right for

Someone who wants one predictable monthly charge, and who will switch each page to the monthly tab before comparing anything.

Look elsewhere if

Anyone reading the first number on the page, because that one requires three months up front.

Other sellers for weight

Rylo Health

Frequently asked questions

What does Rylo Health charge a month?
Semaglutide $139, glutathione $149, GHK-Cu $199, NAD+ $219, tirzepatide $229 and sermorelin $249. Those are the monthly rates, with no membership and free shipping.
Why is the price on the page lower than that?
Because each page opens on its quarterly tab. Sermorelin shows $183 a month, which is $549 billed every three months. Switching to Monthly shows $249.
Who prescribes at Rylo Health?
A US-licensed, board-certified physician who is never named, reviewing a five-minute questionnaire within 24 hours. There is no video call.
Can I get a refund?
Up to a point, and it is a clearer point than most: everything is refundable any time before your first physician consultation. After a prescription, the monthly plan can be canceled any month.

See what Rylo Health prescribes today

Rylo Health sets its own prices, plans and the states it serves. Check them before you start.

Written by Leah Garner from Rylo Health’s own public pages, against the published methodology. No outcome is claimed first-hand and no score is given. A partnership never changes what this page says; see how the site is paid.