What the research measured, goal by goal.
Every claim here is traced to the trial, the label or the paper of record, and we say plainly where the human evidence is thin. The 58 articles are shelved under the goal they were written for.
Compare the peptides on each goal side by side →- Evidence
- 35
- Formats
- 10
- Safety
- 13
Weight
Semaglutide · Tirzepatide · Liraglutide · Orforglipron · Tesamorelin9 articlesWeight peptides →
- 01Evidence · 7 minPeptides for Weight Loss: What the Evidence Shows Beyond Semaglutide and TirzepatideThe peptides with real weight-loss evidence are close relatives of the GLP-1 drugs. Several others sold for fat loss have little or no human data behind them.
- 02Evidence · 6 minRetatrutide: What the Triple-Agonist Trials Show So Far
- 03Evidence · 7 minTesamorelin: What the Egrifta Trials Showed, and What They Did Not
- 04Evidence · 7 minTesamorelin Dosage: What the Egrifta Label States and What the Trials Gave
- 05Safety · 7 minTesamorelin Side Effects: What the Egrifta Trials and Label Recorded
- 06Evidence · 7 minTirzepatide Dosage: The Label's Dose Steps and What the SURMOUNT Trials Used
- 07Evidence · 6 minTirzepatide vs Semaglutide: What the Head-to-Head Trials Found
- 08Evidence · 6 minWegovy Pill: What the Oral Semaglutide Weight Trials Showed
- 09Evidence · 6 minWhat Happens When You Stop Taking Semaglutide: The Trial Extension Data
Sexual health
PT-141 (bremelanotide) · Kisspeptin6 articlesSexual health peptides →
- 01Evidence · 5 minBremelanotide (PT-141): The FDA Approval and What the Trials ShowedBremelanotide is approved for low sexual desire in premenopausal women. Two phase 3 trials found a modest benefit, and 40% of women on it reported nausea.
- 02Safety · 7 minBremelanotide Side Effects: Nausea, Blood Pressure and Skin Darkening
- 03Evidence · 6 minKisspeptin: What Human Studies Show About Libido and Reproductive Hormones
- 04Evidence · 6 minPT 141 Dosage: The Vyleesi Label's 1.75 mg Dose and What Trials Tested
- 05Evidence · 6 minPT 141 for Men: What the Erectile Dysfunction Trials Found
- 06Safety · 6 minPT-141 Nasal Spray: Why Intranasal Bremelanotide Was Dropped in Trials
Longevity
NAD+ · Glutathione · MOTS-c12 articlesLongevity peptides →
- 01Evidence · 6 minEpitalon: What the Telomere Claims Rest OnThe telomere results come from cells in a dish, and the human survival studies used a different substance. The FDA found no clinical data supporting epitalon's safety in people.
- 02Evidence · 6 minGlutathione for Skin: What Trials of Oral, Topical and Injected Forms Found
- 03Evidence · 6 minGlutathione Injections: What the Evidence Shows
- 04Safety · 6 minGlutathione Side Effects: What Injection, IV and Oral Studies Reported
- 05Evidence · 6 minLiposomal Glutathione: Does Oral Glutathione Raise Levels in the Body?
- 06Safety · 5 minMOTS-c Dosage: What Mouse and Human Studies Used, and Why No Dose Is Set
- 07Evidence · 6 minMOTS-c: What the Research Shows in Mice and in People
- 08Evidence · 5 minNAD+ Injections: The Benefits Claimed, and What Studies in People Measured
- 09Evidence · 6 minNAD IV Therapy: What Studies of Intravenous NAD+ in People Measured
- 10Formats · 5 minNAD Nasal Spray: What the Evidence Shows So Far
- 11Formats · 5 minNAD Patches: Can NAD+ Get Through the Skin?
- 12Safety · 6 minNAD Side Effects: What Injection, IV and Oral Precursor Studies Reported
Recovery
Sermorelin · GHK-Cu · BPC-15711 articlesRecovery peptides →
- 01Evidence · 7 minBPC 157 and TB 500 Together: What Any Study Has Tested of the PairOne rat study tested the pair against each alone, and the combination added nothing. In people, the record is 4 survey patients and one FDA adverse-event report.
- 02Safety · 7 minBPC 157 Dosage: Why No Human Dose Exists, and What Studies Used
- 03Evidence · 6 minBPC-157: What Human Evidence Actually Exists
- 04Safety · 5 minBPC-157 Side Effects: What Has Been Recorded in People
- 05Safety · 5 minGHK-Cu Side Effects: What Topical Studies Report, and the Injected Unknowns
- 06Formats · 6 minGHK-Cu: Copper Peptide Evidence, Topical Versus Injected
- 07Evidence · 5 minPeptides for Hair Growth: What the Trials Show
- 08Evidence · 5 minPeptides for Joint Pain: What Human Trials Exist, Compound by Compound
- 09Evidence · 6 minPeptides for Muscle Growth: What Trials of GH Secretagogues Measured
- 10Evidence · 5 minPeptides for Skin: Which Ones Have Human Trials
- 11Evidence · 5 minTB-500: What Is Known, and What Has Never Been Tested
Sleep
Sermorelin13 articlesSleep peptides →
- 01Evidence · 7 minCJC 1295 and Ipamorelin: What Human Studies Exist for the PairEach peptide has a thin human record of its own. No trial of the two taken together has been published or registered, and FDA has flagged safety concerns about both.
- 02Evidence · 6 minDoes Sermorelin Work? What the Human Studies Measured
- 03Evidence · 6 minDSIP Peptide: What Delta Sleep-Inducing Peptide Trials in People Found
- 04Evidence · 7 minGrowth Hormone Peptides: GHRH Analogs vs Ghrelin Mimetics, and Their Evidence
- 05Evidence · 6 minIpamorelin: What the Human Evidence Actually Shows
- 06Safety · 6 minIpamorelin Side Effects: What the Few Human Trials Recorded
- 07Evidence · 7 minPeptides for Sleep: What Human Studies of GHRH and DSIP Found
- 08Evidence · 6 minSermorelin Before and After: What Trials Measured Over Weeks and Months
- 09Formats · 6 minSermorelin Dosage: What the Approved Product and Trials Actually Used
- 10Formats · 6 minSermorelin Nasal Spray: Does GHRH Work Without an Injection?
- 11Safety · 6 minSermorelin Side Effects: What the Trials and FDA Record Report
- 12Evidence · 6 minSermorelin vs Ipamorelin: Two Very Different Evidence Records
- 13Evidence · 7 minTesamorelin vs Sermorelin: Two GHRH Analogs With Very Different Evidence
Before any goal
Written for no single goal, so they apply whichever one you came for: the basics, the law, and what drug labels say about handling a peptide.- 01Are Peptides Legal? FDA Categories, 503A, 503B and "Research Use Only"Safety · 6 min
- 02Are Peptides Safe? It Depends on Which One, and Where It Came FromSafety · 6 min
- 03Bacteriostatic Water for Peptides: What the Labels SayFormats · 5 min
- 04How to Reconstitute Peptides: What the Drug Labels InstructFormats · 6 min
- 05How to Store Peptides: What Four Drug Labels RequireFormats · 5 min
- 06Peptide Injection Sites: Where the Labels Say to InjectFormats · 5 min
- 07What Are Peptides? How They Work, and Why Most Are InjectedFormats · 7 min