TMates
Every plan bundles the medication, the telemedicine visits and coaching into one figure, and the multi-month discounts are arithmetically honest. The claims behind them are not sourced at all.
Review by Craig Palmer, peptide pharmacology writer · Updated September 2026
The short version
TMates is straightforward about money and vague about evidence. Its ladders are real: every advertised saving matches the totals it prints. No study is cited anywhere, and its sermorelin page carries testimonials about a different product.
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TMates is a telemedicine program selling compounded peptides and GLP-1s across all fifty states. It offers sermorelin, NAD+ as an injection or a nasal spray, and compounded semaglutide and tirzepatide. Each product is sold on a one, three, six or twelve-month plan. The program bundles telemedicine visits, coaching and the medication into a single price.
What TMates prescribes, by goal
Weight
- SemaglutideFDA-approved
- Injection (compounded)From $249/mo
- TirzepatideFDA-approved
- Injection (compounded)From $297/mo
Compounded semaglutide starts at $249 a month and tirzepatide at $297, both falling steeply on longer terms. No dose in milligrams is printed for either, so neither can be compared on strength.
Longevity
- NAD+Legal to compound
- Injection (compounded)From $149/mo
- Nasal spray (compounded)From $149/mo
NAD+ is the one product here that publishes what you get. The injection is listed at 1000mg in 5ml, at 200mg per ml, given subcutaneously. It starts at $149 a month and falls to $88 on a twelve-month plan. A nasal format is offered alongside it at the same starting figure.
Recovery
- SermorelinLegal to compound
- Injection (compounded)From $179/mo
Sermorelin starts at $179 a month. Longer plans bring that down: $167 on three months, $150 on six, $129 on twelve. The page prints no dose for it, in milligrams or otherwise, so the monthly figure cannot be turned into a cost per unit.
Sleep
- SermorelinLegal to compound
- Injection (compounded)From $179/mo
Better sleep is listed among the sermorelin benefits, and the page says many patients notice improved sleep quality within the first two to three weeks. No study is attached to that, or to any other claim on the page.
Each “From” figure is the seller’s own starting price, in the unit the seller states. Where a required fee or a package length changes what one month costs, the smaller line under it is our arithmetic, not a figure the seller prints. Compounded preparations are not FDA-approved.
Who prescribes
A licensed clinician
TMates describes medical staff and licensed medical professionals who assess your history and goals. No prescriber is named, and no medical leadership appears on the product pages. It is unusually clear about one thing, though: its footer states plainly that TMates is not a 503A or 503B compounding facility. It says it may offer compounded medicines from registered US pharmacies, without naming which.
You fill in an intake form and then have a telehealth consultation before any prescription. The site frames this as a ninety-second health quiz to check whether you qualify. The program then runs on regular virtual consultations, with coaching and ongoing access folded into the plan price. Shipping is free and you can cancel at any time. One oddity worth knowing: the site says it generally accepts most major insurance plans, which is rare for compounded peptides and sits awkwardly beside its all-inclusive cash pricing.
Are labs required?
Not asked for
No bloodwork is requested before a prescription, and the pages never say when a clinician might order any. For a growth-hormone-axis product that is a real gap, since IGF-1 is the usual baseline measurement.
Ready to start with TMates?
Lowest listed price: NAD+ injection, from $149/mo. Confirm it on the seller’s own site.
What it claims, and what it cites
This is the weak side. The sermorelin page lists benefits with no citation behind any of them: anti-aging, improved body composition, better sleep, enhanced recovery. It asserts a timeline too, saying sleep improves within two to three weeks. Nothing supports it. The page also calls sermorelin a safer alternative to direct HGH, which is a comparative safety claim with no evidence offered. Then there are the testimonials. Both quotes printed under the sermorelin heading are about NAD+ supplements, not sermorelin. The compounding disclaimer, by contrast, is unusually plain.
| On TMates’s site | Source it gives |
|---|---|
| On TMates’s site“Better sleep quality within the first 2-3 weeks” | Source it givesNone given |
| On TMates’s site“A safer alternative to direct HGH supplementation” | Source it givesNone given |
| On TMates’s site“Two patient testimonials under the sermorelin heading” | Source it givesBoth quotes describe NAD+ supplements rather than sermorelin |
| On TMates’s site“Not a 503A or 503B compounding facility” | Source it givesStated directly in the site footer, alongside the compounding disclaimer |
Sold by TMates, not listed here
- Phentermine and the hair and skin lines
- Non-peptide medicines and cosmetic products outside what this site covers.
How it bills
Every plan price includes the medication, the telemedicine visits and coaching, and the site says there are no hidden fees. Shipping is free and cancellation is open. The multi-month savings are worth checking, and they hold up. Sermorelin at three months is $500, which is $167 each and the 7% advertised. Six months is $900, or $150 each and 16%. Twelve months is $1,550, or $129 each and 28%. NAD+ works the same way: $400, $650 and $1,050 give $133, $108 and $88 a month. Each advertised percentage matches the totals printed beside it.
Availability: All 50 states
For and against
- For: Medication, visits and coaching in one price
- For: Advertised savings match the printed totals
- For: NAD+ lists strength, volume and route
- For: States it is not a compounding facility
- Against: No study cited for any claim
- Against: Sermorelin testimonials describe NAD+
- Against: No dose printed for sermorelin
- Against: No prescriber or pharmacy named
The evidence behind what it sells
- Tirzepatide Headache: What the Labels and Trial Results Recorded
- Does NAD Cause Cancer? What Human and Animal Studies Show
- Sermorelin vs HGH: A Signal to the Pituitary or the Hormone Itself
- Does Tirzepatide Make You Tired? What the Trials and Labels Show
- NAD for Parkinson's: What the Human Trials Have Found So Far
- Does Sermorelin Work? What the Human Studies Measured
Right for
Readers who want NAD+ from a service that publishes the strength, and who plan a longer term where the discounts genuinely apply.
Look elsewhere if
Anyone who wants a claim backed by a study, or a sermorelin dose they can compare against another seller.
Other sellers for weight
50 Stars Health
Also prescribes Semaglutide, Tirzepatide.
Actin
Also prescribes Semaglutide, Tirzepatide.
AgelessRx
Also prescribes Semaglutide, Tirzepatide.
TMates
Frequently asked questions
- Does TMates publish a sermorelin dose?
- No. The sermorelin page prints no strength in milligrams and no schedule. Its NAD+ page does both, listing 1000mg in 5ml at 200mg per ml, given subcutaneously.
- Are the TMates multi-month savings real?
- Yes. Each advertised percentage matches the totals on the page. Sermorelin at $500 for three months is $167 a month and the 7% claimed; $1,550 for twelve is $129 a month and the 28% claimed.
- Does TMates cite evidence for its sermorelin claims?
- No study appears on the page. Better sleep, improved body composition and a two-to-three-week timeline are all asserted without a source, and the two testimonials shown describe NAD+ rather than sermorelin.
See what TMates prescribes today
TMates sets its own prices, plans and the states it serves. Check them before you start.