Skip to content
thispeptide

Direct Meds

Direct Meds sells compounded GLP-1s, sermorelin, NAD+ and glutathione, most as a 90-day supply billed monthly. It prints more strengths than most sellers. Its claims are loud, and none is sourced.

Review by Molly Ward, goal-guide writer · Updated September 2026

The short version

Direct Meds is a reasonable choice if you want sermorelin or NAD+ with the strength on the page and no membership fee. The catch is the paperwork. The product pages say cancel anytime, the terms describe a subscription with no refund on medication received, and the claims copy cites nothing.

Disclosure: This Peptide is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. How we make money.

Lowest listed: NAD+ nasal spray, from $119/mo

Every state but Alabama and Mississippi

Visit Direct Meds →

Direct Meds is a cash-pay online prescriber for weight loss, longevity and wellness. Its catalog runs from compounded semaglutide and tirzepatide to sermorelin, NAD+ and glutathione, alongside supplements, hair medicines and skin creams.

What Direct Meds prescribes, by goal

Weight

  • SemaglutideFDA-approved
    • Injection (compounded)From $297/mo
    • Sublingual (compounded)From $249/mo
  • TirzepatideFDA-approved
    • Injection (compounded)From $399/mo
    • Sublingual (compounded)From $299/mo

Semaglutide and tirzepatide come as weekly injections or as sublingual drops. Each is priced on a 90-day supply billed monthly. The sublingual semaglutide page prints its daily dose; the injection pages print none.

Longevity

  • NAD+Legal to compound
    • Nasal spray (compounded)From $119/mo
    • Injection (compounded)From $199/mo
  • GlutathioneLegal to compound
    • Injection (compounded)From $249/mo

NAD+ comes as a daily weekday injection in 500 mg or 1,000 mg strengths, or as a nasal spray at 15 mg per spray. Glutathione is a 200 mg per mL injection into the muscle. Both are cheaper per month on the 90-day supply.

Recovery

  • SermorelinLegal to compound
    • Injection (compounded)From $249/mo

Sermorelin is the recovery product here. The page tells you to reassess with your doctor every three to six months, with labs, but does not say who orders them.

Sleep

  • SermorelinLegal to compound
    • Injection (compounded)From $249/mo

Sermorelin is injected at bedtime, five nights a week. The page prints the dose: 300 mcg a night for the first four weeks, then 600 mcg. It is $249 a month on a 90-day supply, or $299 for a single month plus shipping.

Prices are the seller’s own published starting figures, each in the unit the seller states. Compounded preparations are not FDA-approved.

Who prescribes

A licensed clinician

The site says a U.S.-licensed physician or licensed provider reviews every intake, usually within a day. Prescribers are not named on the product pages. The team page names a physician as chief medical officer, and a nursing team answers questions on demand.

There is no appointment. You take an online quiz and fill in an intake form, and a provider reviews it, often within a few business hours. After that, a care team and on-demand nurses handle questions by message.

Are labs required?

Not required to start

No product page requires labs before you start, and no lab price is published. The sermorelin page suggests a review with your doctor every three to six months, based partly on labs.

Ready to start with Direct Meds?

Lowest listed price: NAD+ nasal spray, from $119/mo. Confirm it on the seller's own site.

Visit Direct Meds →

What it claims, and what it cites

The copy is confident and unsourced. Sermorelin is called clinically proven, with visceral fat said to fall by months three to six. NAD+ is sold as a biohack for focus and memory. The GLP-1 pages speak of meaningful, sustained weight loss. No page links a study.

On Direct Meds’s siteSource it gives
On Direct Meds’s site“Clinically Proven Peptide Therapy”Source it givesNone given
On Direct Meds’s site“Months 3–6: Visceral fat trends down, lean mass trends up”Source it givesNone given
On Direct Meds’s site“Enhance cognitive function, focus, and memory”Source it givesNone given
On Direct Meds’s site“High bioavailability (89%)”Source it givesNone given

Sold by Direct Meds, not listed here

BPC-157
On no 503A list (removed from Category 2 in April 2026, never in Category 1). The FDA's compounding advisory committee voted 8–6 (one abstention) in July 2026 to favor listing it; the vote is a recommendation, not binding on the FDA, and pharmacies may not compound it until final rulemaking.
Tesamorelin
Approved only as Egrifta, for excess abdominal fat in adults with HIV-associated lipodystrophy. Its label says it is not indicated for weight loss. Egrifta became a biologic (BLA) on March 23, 2020, and FDA says compounded versions of these products do not qualify for the 503A or 503B compounding exemptions.
Supplements, hair and skin products
Appetite supplements, finasteride, minoxidil and face and pain creams. None is a peptide.
Estrogen, progesterone and DHEA
Hormone treatments, which this site does not cover.

How it bills

Most products are priced per month on a 90-day supply that ships at once, and a 30-day supply costs more. The product pages promise no membership fee and cancel anytime, and shipping is free. The terms describe a subscription that renews every 30 days until you turn off auto-refill at least 48 hours before the next charge. Medication you have received is not refunded, and a return carries a $35 disposal fee.

Availability: Every state but Alabama and Mississippi

LegitScript: seal displayed on the seller’s site

For and against

  • For: Prints sermorelin and NAD+ strengths
  • For: NAD+ as injection or nasal spray
  • For: No membership fee
  • For: No appointment needed
  • Against: Terms describe an auto-renewing plan
  • Against: No refund on medication received
  • Against: Claims cite no study
  • Against: Best prices need a 90-day supply

The evidence behind what it sells

Right for

Readers who want sermorelin or NAD+ with the strength printed, and who are happy to take three months of supply in one box.

Look elsewhere if

Anyone who wants sourced claims, a month-to-month price as the headline, or a clear refund if they stop early.

Other sellers for weight

Direct Meds

Frequently asked questions

Does Direct Meds require blood work for sermorelin?
Not to start. The sermorelin page suggests reviewing your progress with your doctor every three to six months, partly on labs.
Is a Direct Meds order a subscription?
The terms say yes for certain products. They renew every 30 days until you turn off auto-refill at least 48 hours before the next charge.
Does Direct Meds sell NAD+ as a nasal spray?
Yes. It sells NAD+ as an injection or as a nasal spray, and the spray is cheaper per month on the 90-day supply.

See what Direct Meds prescribes today

Direct Meds sets its own prices, plans and the states it serves. Check them before you start.

Visit Direct Meds →
Written by Molly Ward from Direct Meds’s own public pages, against the published methodology. No outcome is claimed first-hand and no score is given. A partnership never changes what this page says; see how the site is paid. Last updated September 2026.